Protein targets of thiazolidinone derivatives in Toxoplasma gondii and insights into their binding to ROP18
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چکیده
منابع مشابه
Synthesis of thiosemicarbazone and 4-thiazolidinone derivatives and their in vitro anti-Toxoplasma gondii activity.
Thiosemicarbazone and 4-thiazolidinone derivatives were synthesized in one and two step, respectively, from thiosemicarbazide, in satisfactory yields. Then, the synthesized compounds were submitted to evaluation against host cells infected with Toxoplasma gondii. The present studies showed that thiosemicarbazones 2 and 4-thiazolidinone derivatives 3 were effective against intracellular T. gondii.
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2018
ISSN: 1471-2164
DOI: 10.1186/s12864-018-5223-7